Directory

Journal devoted to the neurobiology of stress

Social-evaluative stressors—experiences in which people feel they could be judged negatively—pose a major threat to adolescent mental health1,2,3 and can cause young people to disengage from stressful pursuits, resulting in missed opportunities to acquire valuable skills. Here we show that replicable benefits for the stress responses of adolescents can be achieved with a short (around 30-min), scalable 'synergistic mindsets' intervention. This intervention, which is a self-administere […]

About This Workshop 70-90% of all primary care visits in America are related to chronic stress and stress-related illnesses such as anxiety, depression, PTS, heart disease, headaches, GI disruptions, and more. In the next workshop of the Scientific Research series, Yoga Alliance Director of Research, Dr. Sat Bir Singh Khalsa is joined by Dr. John Denninger, Director of Research at the Benson-Henry Institute for Mind Body Medicine at Massachusetts General Hospital and Harvard Universit […]

In light of World Sleep Day this month, this week’s guest post features Valerie Teh, Calmer’s Client Manager and Self-Care Practitioner, who shares her expertise on how to explore and embrace intelligent rest to enhance quality sleep and nurture your overall wellbeing.

Background and aim Mental stress represents a pivotal factor in cardiovascular diseases. The mechanism by which stress produces its deleterious effects is still under study, but one of the most explored pathways is inflammation-aging and cell senescence. In this scenario, circulating microRNAs appear to be regulatory elements of the telomerase activity and alternative splicing within the nuclear factor kappa-light-chain-enhancer (NF-κB) network. Anti-stress techniques appeared to be […]

Mind–body medicine is an evidence-based approach to health and healing that focuses on interactions between the mind, body, and behavior. It encompasses a wide range of interventions that are similar yet different in meaningful ways. Mindfulness and relaxation practices are 2 mind–body techniques that have similarities and differences; however, these techniques are often used or discussed interchangeably, such that the differences between them become obscured. A greater understanding […]

Relaxation helps to reduce physical, mental, and emotional pressure. Relaxation techniques generally enable a person to obtain calmness and well-being by reducing stress, anxiety, or anger. When a person becomes calm the body reacts physiologically, producing the so-called Relaxation Response (RResp) which affects the organism in a positive manner, no matter if it is during a state of relaxation or in the middle of a stressful period. The goal of this paper is to design a system capab […]

Background: Obsessive-compulsive disorder (OCD) is often a life-long disorder with high psychosocial impairment. Serotonin reuptake inhibitors (SRIs) are the only FDA approved drugs, and approximately 50% of patients are non-responders when using a criterion of 25% to 35% improvement with the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS). About 30% are non-responders to combined first-line therapies (SRIs and exposure and response prevention). Previous research (one open, one randomi […]

Stress is a term used to define the body’s physiological and psychological reactions to circumstances that require behavioral adjustment [1,2,3], and the relaxation response is a psychophysiological state that is opposite to that of the stress or fight–flight response [4]. A variety of mind/body techniques can be used to elicit a relaxation response and achieve the therapeutic effects associated with reduced blood pressure. For example, researchers at the Cochrane Review [5] investiga […]

Objective: Mind–body practices that elicit the relaxation response (RR) have been demonstrated to reduce blood pressure (BP) in essential hypertension (HTN) and may be an adjunct to antihypertensive drug therapy. However, the molecular mechanisms by which the RR reduces BP remain undefined. Design: Genomic determinants associated with responsiveness to an 8-week RR-based mind–body intervention for lowering HTN in 13 stage 1 hypertensive patients classified as BP responders and 11 as n […]