Category: Addiction

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Chronic Stress, Drug Use, and Vulnerability to ...
Rajita Sinha
Annals of the New York Academy of Sciences
Stress is a well-known risk factor in the development of addiction and in addiction relapse vulnerability. A series of population-based and epidemiological studies have identified specific stressors and individual-level variables that are predictive of substance use and abuse. Preclinical research also shows that stress exposure enhances drug self-administration and reinstates drug seeking in drug-experienced animals. The deleterious effects of early life stress, child maltreatment, a […]