Journal
Journal of Traditional and Complementary Medicine
Background and aim Mental stress represents a pivotal factor in cardiovascular diseases. The mechanism by which stress produces its deleterious effects is still under study, but one of the most explored pathways is inflammation-aging and cell senescence. In this scenario, circulating microRNAs appear to be regulatory elements of the telomerase activity and alternative splicing within the nuclear factor kappa-light-chain-enhancer (NF-κB) network. Anti-stress techniques appeared to be […]
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Global Advances in Integrative Medicine and Health
Mind–body medicine is an evidence-based approach to health and healing that focuses on interactions between the mind, body, and behavior. It encompasses a wide range of interventions that are similar yet different in meaningful ways. Mindfulness and relaxation practices are 2 mind–body techniques that have similarities and differences; however, these techniques are often used or discussed interchangeably, such that the differences between them become obscured. A greater understanding […]
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IEEE Access
Relaxation helps to reduce physical, mental, and emotional pressure. Relaxation techniques generally enable a person to obtain calmness and well-being by reducing stress, anxiety, or anger. When a person becomes calm the body reacts physiologically, producing the so-called Relaxation Response (RResp) which affects the organism in a positive manner, no matter if it is during a state of relaxation or in the middle of a stressful period. The goal of this paper is to design a system capab […]
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Frontiers in Psychiatry
Background: Obsessive-compulsive disorder (OCD) is often a life-long disorder with high psychosocial impairment. Serotonin reuptake inhibitors (SRIs) are the only FDA approved drugs, and approximately 50% of patients are non-responders when using a criterion of 25% to 35% improvement with the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS). About 30% are non-responders to combined first-line therapies (SRIs and exposure and response prevention). Previous research (one open, one randomi […]
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Journal Alternative and Complementary Medicine
Objective: Mind–body practices that elicit the relaxation response (RR) have been demonstrated to reduce blood pressure (BP) in essential hypertension (HTN) and may be an adjunct to antihypertensive drug therapy. However, the molecular mechanisms by which the RR reduces BP remain undefined. Design: Genomic determinants associated with responsiveness to an 8-week RR-based mind–body intervention for lowering HTN in 13 stage 1 hypertensive patients classified as BP responders and 11 as n […]
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AAAS Eureka Alert
Researchers identified genes and biological pathways linked to immune regulation, metabolism, and circadian rhythm in people who reduced their hypertension after eight-week relaxation response training
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PLOS ONE
Introduction Irritable Bowel Syndrome (IBS) and Inflammatory Bowel Disease (IBD) can profoundly affect quality of life and are influenced by stress and resiliency. The impact of mind-body interventions (MBIs) on IBS and IBD patients has not previously been examined. Methods Nineteen IBS and 29 IBD patients were enrolled in a 9-week relaxation response based mind-body group intervention (RR-MBI), focusing on elicitation of the RR and cognitive skill building. Symptom questionnaires […]
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PLOS ONE
The relaxation response (RR) is the counterpart of the stress response. Millennia-old practices evoking the RR include meditation, yoga and repetitive prayer. Although RR elicitation is an effective therapeutic intervention that counteracts the adverse clinical effects of stress in disorders including hypertension, anxiety, insomnia and aging, the underlying molecular mechanisms that explain these clinical benefits remain undetermined. To assess rapid time-dependent (temporal) genomic […]
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Journal of Integrative and Complementary Medicine
Several hundred peer-reviewed studies in the past 20 years have shown that the relaxation response and mind–body interventions are clinically effective in the treatment of many health problems that are caused or made worse by stress. Recent studies show that mind–body interventions may improve prognosis in coronary heart disease and can enhance immune functioning. It is hypothesized that mind–body interventions reduce sympathetic nervous system activation and increase parasympathetic […]
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Behaviour Research Therapy
Ten of thirteen original participants with Irritable Bowel Syndrome (IBS) participated in a one year follow-up study to determine whether the effects of Relaxation Response Meditation (RRM) on IBS symptom reduction were maintained over the long-term. From pre-treatment to one-year follow-up, significant reductions were noted for the symptoms of abdominal pain (p=0.017), diarrhea (p=0.045), flatulence (p=0.030), and bloating (p=0.018). When we examined changes from the original three m […]