Neurobiology of Stress

Meditation is a conscious mental process that induces a set of integrated physiologic changes termed the relaxation response. Functional magnetic resonance imaging (fMRI) was used to identify and characterize the brain regions that are active during a simple form of meditation. Significant (p<10(-7)) signal increases were observed in the group-averaged data in the dorsolateral prefrontal and parietal cortices, hippocampus/parahippocampus, temporal lobe, pregenual anterior cingulate […]

A prospective investigation was designed to test whether the altered behavior of the regular practice of a relaxation, meditational technique might lower blood pressure in 22 borderline hypertensive subjects. The investigation was unbiased with regard to the presence of antihypertensive agents; subject familiarity with blood pressure measurement or with the observer; observer error; and the effects of blood pressure variability. During the control period, blood pressures averaged 146. […]

It is hypothesized that situations requiring continuous behavioral adjustment activate an integrated, hypothalamic response, the emergency reaction. The frequent elicitation of the physiologic changes associated with the emergency reaction has been implicated in the development of diseases such as hypertension. Prevention and treatment of these diseases may be through the use of the relaxation response, an integrated hypothalamic response whose physiologic changes appear to be the cou […]