Genomic Counter-Stress Changes Induced by the Relaxation Response

Authors
Jeffery A. Dusek, Hassan H. Otu, Ann L. Wohlhueter, Manoj Bhasin, Luiz F. Zerbini, Marie G. Joseph, Herbert Benson, Towia A. Libermann
Publication
PLOS ONE
Abstract

Mind-body practices that elicit the relaxation response (RR) have been used worldwide for millennia to prevent and treat disease. The RR is characterized by decreased oxygen consumption, increased exhaled nitric oxide, and reduced psychological distress. It is believed to be the counterpart of the stress response that exhibits a distinct pattern of physiology and transcriptional profile. We hypothesized that RR elicitation results in characteristic gene expression changes that can be used to measure physiological responses elicited by the RR in an unbiased fashion.

Related Listings
Health Outcomes and a New Index of Spiritual Ex...
Authors
Jared D. Kass, Richard Friedman, Jane Leserman, Patricia C. Zuttermeister, Herbert Benson
Journal
Journal for the Scientific Study of Religion
·
Clinical observations suggesting a relationship between spiritual experiences, life purpose and satisfaction, and improvements in physical health led to the development of an Index of Core Spiritual Experience (INSPIRIT). Data from 83 medical outpatients showed the INSPIRIT to have a strong degree of internal reliability and concurrent validity. Multiple regression analyses showed the INSPIRIT to be associated with: (1) increased life purpose and satisfaction, a health-promoting attit […]
The efficacy of progressive relaxation in syste...
Authors
Martha M. Greenwood, Herbert Benson
Journal
Behavior Research and Therapy
·
The theoretical basis of systematic desensitization is reciprocal inhibition in which an alternative, competitive response to anxiety is conditioned to arousal-producing, phobic stimuli. Abbreviated training in progressive relaxation is believed to serve as a competitive response to anxiety by decreasing autonomic nervous system activity. However, physiologic studies of progressive relaxation have not substantiated that its practice is associated with such decreased autonomic activity […]
Relaxation Response and Resiliency Training and...
Authors
James E. Stahl, Michelle L. Dossett, A. Scott LaJoie, John W. Denninger, Darshan H. Mehta, Roberta Goldman, Gregory L. Fricchione, Herbert Benson
Journal
PLOS ONE
·
Background Poor psychological and physical resilience in response to stress drives a great deal of health care utilization. Mind-body interventions can reduce stress and build resiliency. The rationale for this study is therefore to estimate the effect of mind-body interventions on healthcare utilization. Objective Estimate the effect of mind body training, specifically, the Relaxation Response Resiliency Program (3RP) on healthcare utilization. Design Retrospective controlled […]