Publication
The International Journal of Psychiatry in Medicine
6(1-2)
Abstract
It is hypothesized that situations requiring continuous behavioral adjustment activate an integrated, hypothalamic response, the emergency reaction. The frequent elicitation of the physiologic changes associated with the emergency reaction has been implicated in the development of diseases such as hypertension. Prevention and treatment of these diseases may be through the use of the relaxation response, an integrated hypothalamic response whose physiologic changes appear to be the counterpart of the emergency reaction. This article describes the basic elements of techniques which elicit the relaxation response and discusses the results of clinical investigations which employ the relaxation response as a therapeutic intervention.
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Science
Sympathetic nervous system activity was assessed in experimental and control subjects who were exposed to graded orthostatic and isometric stress during monthly hospital visits. After the first session, the experimental subjects practiced a technique that elicited the relaxation response. Their concentrations of plasma norepinephrine during subsequent graded stresses were significantly higher. No such changes were noted in the control group. These results were then replicated in the c […]
Journal
Annals of the New York Academy of Sciences
A wakeful hypometabolic state accompanies the practice of a relaxational, meditation technique called Transcendental Meditation. The state is characterized by decreased oxygen consumption, carbon dioxide elimination, respiratory rate and minute ventilation, with no change in respiratory quotient. Arterial blood pH and base excess decrease slightly while arterial blood lactate markedly decreases. Systolic, diastolic, and mean arterial blood pressures remain unchanged. The electroenceph […]
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Journal Alternative and Complementary Medicine
Objective: Mind–body practices that elicit the relaxation response (RR) have been demonstrated to reduce blood pressure (BP) in essential hypertension (HTN) and may be an adjunct to antihypertensive drug therapy. However, the molecular mechanisms by which the RR reduces BP remain undefined. Design: Genomic determinants associated with responsiveness to an 8-week RR-based mind–body intervention for lowering HTN in 13 stage 1 hypertensive patients classified as BP responders and 11 as n […]