Publication
PLOS ONE
Abstract
Mind-body practices that elicit the relaxation response (RR) have been used worldwide for millennia to prevent and treat disease. The RR is characterized by decreased oxygen consumption, increased exhaled nitric oxide, and reduced psychological distress. It is believed to be the counterpart of the stress response that exhibits a distinct pattern of physiology and transcriptional profile. We hypothesized that RR elicitation results in characteristic gene expression changes that can be used to measure physiological responses elicited by the RR in an unbiased fashion.
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Journal
Annals of the New York Academy of Sciences
A wakeful hypometabolic state accompanies the practice of a relaxational, meditation technique called Transcendental Meditation. The state is characterized by decreased oxygen consumption, carbon dioxide elimination, respiratory rate and minute ventilation, with no change in respiratory quotient. Arterial blood pH and base excess decrease slightly while arterial blood lactate markedly decreases. Systolic, diastolic, and mean arterial blood pressures remain unchanged. The electroenceph […]
Journal
Complementary Therapies in Medicine
Background Transcendental meditation (TM) is a stress reduction technique that can potentially lower blood pressure (BP) safely. The American Heart Association recommends that TM may be considered in clinical practice. Objective To provide an overview of all systematic reviews and meta-analyses of TM on BP for evidence-informed clinical decision making. Method Systematic searches of PubMed, EBSCOhost, Cochrane Library, Web of Science, Embase, and PsycINFO for all systematic rev […]
Journal
Frontiers in Psychiatry
Background: Obsessive-compulsive disorder (OCD) is often a life-long disorder with high psychosocial impairment. Serotonin reuptake inhibitors (SRIs) are the only FDA approved drugs, and approximately 50% of patients are non-responders when using a criterion of 25% to 35% improvement with the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS). About 30% are non-responders to combined first-line therapies (SRIs and exposure and response prevention). Previous research (one open, one randomi […]