Category: Hypertension

Objective: Mind–body practices that elicit the relaxation response (RR) have been demonstrated to reduce blood pressure (BP) in essential hypertension (HTN) and may be an adjunct to antihypertensive drug therapy. However, the molecular mechanisms by which the RR reduces BP remain undefined. Design: Genomic determinants associated with responsiveness to an 8-week RR-based mind–body intervention for lowering HTN in 13 stage 1 hypertensive patients classified as BP responders and 11 as n […]

Researchers identified genes and biological pathways linked to immune regulation, metabolism, and circadian rhythm in people who reduced their hypertension after eight-week relaxation response training

We previously reported reduced blood pressure, psychological symptoms, and other cardiac risk factors in hypertensive patients who participated in a nonpharmacologic, outpatient behavioral program. The present study is a 3 to 5 year follow-up of 59 (60%) of the same patients (who served as their own controls) to assess continued efficacy of the program. At entry into the study, patients had hypertension for a median of 6 years. Therefore, it is unlikely that placebo effect could expla […]

Hypertension is one of the leading health problems in the United States. It is commonly accepted that as many as 60 million Americans have hypertension, with the majority (>70%) having mild elevations (diastolic pressure range, 90-104 mm Hg). The treatment of hypertension accounts for more office visits to health care providers and more treatment than any other medical diagnosis. A 1980 National Institutes of Health survey showed that about 2% of visits to health care providers wer […]