Neurobiology of Stress

A wakeful hypometabolic state may be induced by simple, non-cultic mental techniques or by traditional meditational practices. The hypometabolic state seems to represent an integrated hypothalamic response ("relaxation response") which is consistent with a state of decreased sympathetic-nervous-system activity. A prospective investigation was designed to test whether regular elicitation of the relaxation response might lower blood-pressures in hypertensive patients who were maintained […]

To determine whether decreased sympathetic-nervous-system activity achieved by the relaxation response could decrease premature ventricular contractions (P.V.C.S), eleven ambulatory patients with proven, stable ischæmic heart-disease and P.V.C.s were investigated. The patients, who were taking no medication for the P.V.C.S, were trained to elicit regularly the relaxation response through a non-cultic psychological technique. The frequency of the P.V.C.s was measured by computer analys […]

Therapeutic interventions that incorporate training in mindfulness meditation have become increasingly popular, but to date, little is known about neural mechanisms associated with these interventions. Mindfulness-Based Stress Reduction (MBSR), one of the most widely used mindfulness training programs, has been reported to produce positive effects on psychological well-being and to ameliorate symptoms of a number of disorders. Here, we report a controlled longitudinal study to investi […]